In-bag vs out-of-bag intraocular lens implantation for ectopia lentis: prospective comparative study
Linghao Song1, Yinuo Wen, Yan Liu
1From the Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China (Song, Wen, Liu, X. Wang, Zexu Chen, Jia, T. Chen, Jiang); Key laboratory of Myopia and Related Eye Diseases, NHC, Shanghai, China (Song, Wen, Liu, X. Wang, Zexu Chen, Jia, T. Chen, Jiang); Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China (Song, Wen, Liu, X. Wang, Zexu Chen, Jia, T. Chen, Jiang); Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China (Song, Wen, Liu, X. Wang, Zexu Chen, Jia, T. Chen, Jiang); Department of Ophthalmology, The First Affiliated Hospital of Northwest University, Xi'an City, Shaanxi Province, China (R. Wang); Shanghai Medical College, Fudan University, Shanghai, China (Zhangrui Chen).
Both in-bag and out-of-bag surgeries effectively treat congenital ectopia lentis (CEL). In-bag surgery showed slower axial length growth, while age, not surgical method, impacted visual outcomes.
Area of Science:
- Ophthalmology
- Surgical Innovation
- Pediatric Eye Care
Background:
- Congenital ectopia lentis (CEL) presents unique challenges in visual rehabilitation.
- Understanding the comparative efficacy of different surgical techniques is crucial for optimizing patient outcomes.
Purpose of the Study:
- To compare the short-term and long-term visual outcomes of in-bag versus out-of-bag surgical methods for congenital ectopia lentis (CEL).
Main Methods:
- A prospective comparative study involving 4 groups: children and adults undergoing either in-bag or out-of-bag surgery.
- Follow-up assessments included corrected distance visual acuity (CDVA), axial length (AL) growth, and prediction error (PE).
Main Results:
- No significant difference in CDVA or PE between surgical methods within the same age group.
- Adults achieved better CDVA than children, though with greater myopic drift.
- In-bag surgery demonstrated a reduced rate of axial length (AL) growth compared to out-of-bag surgery.
Conclusions:
- Both in-bag and out-of-bag surgeries are safe and effective for CEL.
- Visual outcomes (CDVA, PE) are primarily age-dependent, not surgical method-dependent.
- In-bag surgery offers a benefit in slowing axial length growth; early amblyopia treatment is vital for visual recovery.
