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Related Experiment Video

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De Quervain Tenosynovitis Detected by Blood Pool SPECT/CT Using New 3D-ring CZT System.

Yacine El Yaagoubi1, Caroline Prunier-Aesch1, Manuel Couchot2

  • 1Department of Nuclear Medicine.

Clinical Nuclear Medicine
|December 23, 2025
PubMed
Summary

New 3D-ring CZT bone scintigraphy effectively detected De Quervain tenosynovitis and thumb arthritis in a wrist pain patient. This advanced imaging highlights its potential for identifying extraosseous conditions beyond bone fractures.

Keywords:
3D-ring CZT SPECT/CTDe Quervain tenosynovitisblood pool SPECT/CTbone scintigraphywrist

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Area of Science:

  • Nuclear Medicine
  • Radiology
  • Musculoskeletal Imaging

Background:

  • Wrist pain is a common complaint, often associated with radial styloid stress fractures.
  • De Quervain tenosynovitis is a frequent cause of wrist and thumb pain.
  • Advanced SPECT/CT technology offers potential for improved diagnostic accuracy.

Purpose of the Study:

  • To evaluate the utility of 99mTc-HDP bone scintigraphy with a 3D-ring CZT system in diagnosing wrist pain.
  • To assess the capability of blood pool SPECT/CT in detecting extraosseous findings, specifically tendinopathies.
  • To highlight the diagnostic performance of new SPECT/CT technology in a case of suspected radial styloid fracture.

Main Methods:

  • A 58-year-old woman with right wrist pain underwent 99mTc-HDP bone scintigraphy using a 3D-ring CZT system.
  • Blood pool and late-phase SPECT/CT imaging were performed.
  • Ultrasound imaging was utilized for confirmation.

Main Results:

  • Blood pool SPECT/CT revealed intense hyperemia in the first extensor compartment, indicative of De Quervain tenosynovitis.
  • Late-phase SPECT/CT identified right thumb arthritis.
  • Ultrasound confirmed the diagnosis of De Quervain tenosynovitis.

Conclusions:

  • Blood pool SPECT/CT with a 3D-ring CZT system can effectively detect De Quervain tenosynovitis.
  • This advanced imaging technique shows promise for identifying extraosseous abnormalities, including tendinopathies, in patients with wrist pain.
  • The findings underscore the value of advanced SPECT/CT in comprehensive wrist pain evaluation.