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Updated: May 19, 2026

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
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Published on: November 23, 2019

Iliotibial Band Syndrome Detected by Bloodpool SPECT/CT Using New 3D-Ring CZT System.

Yacine El Yaagoubi1, Caroline Prunier-Aesch1, Olivier Wargnier2

  • 1Departments of Nuclear Medicine.

Clinical Nuclear Medicine
|May 18, 2026
PubMed
Summary

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De Quervain Tenosynovitis Detected by Blood Pool SPECT/CT Using New 3D-ring CZT System.

Clinical nuclear medicine·2025

New 3D-ring CZT SPECT/CT imaging effectively identified iliotibial band syndrome (ITBS) in a runner with knee pain. This advanced imaging shows promise for diagnosing extraosseous conditions beyond bone stress fractures.

Area of Science:

  • Nuclear Medicine
  • Radiology
  • Sports Medicine

Background:

  • Knee pain is common in runners, often presenting diagnostic challenges.
  • Iliotibial band syndrome (ITBS) is a frequent cause of lateral knee pain.
  • Distinguishing ITBS from bone stress injuries can be difficult with conventional imaging.

Purpose of the Study:

  • To evaluate the utility of 99mTc-HDP bone scintigraphy with a 3D-ring CZT SPECT/CT system.
  • To assess the capability of blood pool SPECT/CT in identifying extraosseous pathology.
  • To demonstrate the potential of this new imaging system for diagnosing ITBS.

Main Methods:

  • A 59-year-old female runner with left knee pain underwent 99mTc-HDP bone scintigraphy.
  • Imaging utilized a novel 3D-ring CZT SPECT/CT system (StarGuide).
Keywords:
3D-ring CZT SPECT/CTbloodpool SPECT/CTbone scintigraphyiliotibial band syndrome (ITBS)lateral femoral condyle

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  • Blood pool and late-phase SPECT/CT were analyzed for abnormalities.

    • Main Results:

    • Blood pool SPECT/CT revealed hyperemia consistent with ITBS near the lateral femoral condyle.
    • Late-phase SPECT/CT showed no abnormalities in the bone.
    • Subsequent MRI confirmed the diagnosis of ITBS.

    Conclusions:

    • Blood pool SPECT/CT using a 3D-ring CZT system can detect hyperemia indicative of ITBS.
    • This technique offers valuable insights into extraosseous causes of knee pain.
    • Advanced SPECT/CT imaging shows potential for diagnosing conditions like ITBS in athletes.