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Blood Pool SPECT/CT Using New 3D-ring CZT System in Knee Bursitis.

Yacine El Yaagoubi1, Caroline Prunier-Aesch, Laurent Philippe

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|May 4, 2026
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Summary

New 3D-ring CZT SPECT/CT imaging effectively identified infrapatellar bursitis and patellar tendinopathy in a patient with knee pain. This advanced bone scintigraphy technique aids in diagnosing extraosseous knee conditions.

Keywords:
3D-ring CZT SPECT/CTblood pool SPECT/CTbone scintigraphybursaknee bursitispatellar tendinopathy

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Area of Science:

  • Nuclear Medicine
  • Radiology
  • Musculoskeletal Imaging

Background:

  • Complex regional pain syndrome is a diagnostic challenge, often requiring advanced imaging beyond plain radiography.
  • Knee pain can stem from various sources, including bursitis and tendinopathy, which may not be evident on standard X-rays.
  • Technological advancements in nuclear medicine imaging systems are crucial for improving diagnostic accuracy in musculoskeletal disorders.

Purpose of the Study:

  • To evaluate the utility of a novel 3D-ring CZT SPECT/CT system for diagnosing knee pain.
  • To assess the capability of blood pool SPECT/CT in identifying extraosseous pathologies, such as infrapatellar bursitis.
  • To demonstrate the effectiveness of advanced bone scintigraphy in detecting associated conditions like patellar tendinopathy.

Main Methods:

  • A 63-year-old male patient with left knee pain underwent 99mTc-HDP bone scintigraphy utilizing a 3D-ring CZT SPECT/CT system (StarGuide).
  • Blood pool and late-phase SPECT/CT imaging were performed to assess vascularity and focal uptake.
  • Plain radiography was conducted initially, yielding normal results.

Main Results:

  • Blood pool SPECT/CT revealed intense hyperemia along the patellar tendon, indicative of infrapatellar bursitis.
  • Late-phase SPECT/CT demonstrated focal increased radiotracer uptake on the tibial tuberosity, suggesting associated patellar tendinopathy.
  • The 3D-ring CZT system provided detailed anatomical and functional information beyond conventional imaging.

Conclusions:

  • Blood pool SPECT/CT imaging with the new 3D-ring CZT system is highly effective in diagnosing infrapatellar bursitis.
  • This advanced scintigraphy technique successfully identified concurrent patellar tendinopathy, highlighting its value in complex knee pain evaluation.
  • The study underscores the potential of 3D-ring CZT SPECT/CT to detect relevant extraosseous knee conditions, improving diagnostic capabilities.