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B cell targeted CAR-T therapy for autoimmune diseases

Qi Li1, Ning Zhao1, Ruitao Hou1

  • 1Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.

Frontiers of Medicine
|December 26, 2025
PubMed
Abstract

Keywords:
autoimmune diseaseschimeric antigen receptor-T therapyclinical applicationimmune-mediated necrotizing myopathylymphodepletionmultiple sclerosismyasthenia gravisrheumatoid arthritissystemic lupus erythematosussystemic sclerosis

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