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Updated: Jan 7, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

Bio-inspired nacre-like glass flake/polymer composites with antibacterial function and translucent appearance.

Huijun Sun¹, Aukrit Luangpattarawong², Parinaz Tabrizian²

¹Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction & College and Hospital of Stomatology, Guangxi Medical University, Nanning 530021, China; Bristol Dental School, University of Bristol, UK.

Journal of Dentistry

|January 4, 2026

Summary

A novel bio-inspired nacre-like composite was developed for dental applications, offering enhanced mechanical strength, antibacterial properties, and aesthetic translucency. This material mimics natural nacre for improved dental restorations.

Keywords:

Antimicrobial function Fracture toughness Glass flake Nacre-like composite Translucency

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Area of Science:

Materials Science
Biomaterials Engineering
Dental Materials

Background:

Dental composites require improved mechanical properties, antibacterial function, and aesthetics.
Bio-inspired materials offer promising solutions for advanced dental applications.

Purpose of the Study:

To develop a bio-inspired nacre-like glass flake/polymer composite.
To enhance mechanical properties, antibacterial function, and aesthetic appearance for dental use.

Main Methods:

Fabrication of nacre-like composites using self-assembly and in-situ polymerization.
Optimization of dimethylaminohexadecyl methacrylate (DMAHDM) content.
Evaluation of mechanical properties (flexural strength, elastic modulus, fracture toughness), antibacterial activity, and translucency.

Main Results:

Composites exhibited nacre-like layered microstructures.
1.5 wt% DMAHDM composite showed flexural strength comparable to benchmark aesthetic dental composites (126.97 MPa).
Achieved bio-inspired mechanical properties (elastic modulus similar to dentine), excellent damage tolerance, significant antibacterial function against Streptococcus mutans, and translucency similar to human enamel.

Conclusions:

A bio-inspired nacre-like glass flake/polymer composite was successfully developed.
The composite demonstrates excellent mechanical properties, crack resistance, antibacterial activity, and aesthetic appeal.
This material holds significant potential for aesthetic dental applications.