Ambient mass spectrometric analysis of perfluorosulfonic acids with a covalently immobilized irreversible
Xu-Qin Ran1, Qian-Ying Mao2, Xiu-Ping Yan3
1State Key Laboratory of Food Science and Resource, Jiangnan University, Wuxi, 214122, China; Department of Light Chemical Engineering, Jiangnan University, Wuxi, 214122, China.
Abstract:
As an emerging potential pollutant, perfluorosulfonic acids (PFSAs) pose a challenge in developing efficient analytical methods to meet diverse practical requirements. Herein, an irreversible trifluoromethyl-functionalized covalent organic framework (TFPPA-CF3) is prepared via condensation of 1,3,5-trimethylphloroglucinol and 2,5-diaminobenzo-trifluoride, and then covalently immobilized on stainless steel fiber for solid-phase microextraction (SPME) of PFSAs. The irreversibility of TFPPA-CF3 and its covalent bonding way ensure outstanding probe stability, while multiple interactions (F-F interaction, hydrophobic interaction, and electrostatic interaction) confer high affinity for PFSAs extraction. Finally, an ambient mass spectrometric analytical method using TFPPA-CF3-based SPME is developed for direct and chromatography-free detection of trace PFSAs, achieving detection limits of 0.71-1.11 ng L-1 and linear ranges of 10-10000 ng L-1. The TFPPA-CF3 probe exhibits good stability, preserving over 90 % of extraction efficiency after 100 recycles. The spiked recoveries of the developed method range from 91.6 % to 111.8 % in real-world samples, confirming its practical applicability.
