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Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
A case of Stevens-Johnson syndrome triggered by Mycoplasma infection
Atsushi Uenoyama1, Hideaki Hirai1, Yuko Saito1
1Division of Oral and Maxillofacial Surgery, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University.
Abstract:
Stevens-Johnson syndrome (SJS) is a rare, potentially life-threatening mucocutaneous disorder, which is often triggered by infections such as Mycoplasma pneumoniae. This report describes a 19-year-old woman who initially presented with oral erosions and painful blisters, along with fever and cough. Oral lesions preceded skin and ocular involvement, and tests confirmed Mycoplasma-associated SJS. She responded to steroid pulse therapy but relapsed at 3 months and was then successfully treated. Oral manifestations may be early SJS indicators; thus, prompt recognition and interdisciplinary care by oral health professionals are vital for improving clinical outcomes.
Insights
Stevens-Johnson syndrome (SJS), a severe mucocutaneous disorder, can be indicated by early oral lesions. Prompt recognition and interdisciplinary care are vital for Mycoplasma-associated SJS, as demonstrated in a case report.
Area of Science:
- Dermatology
- Infectious Diseases
- Oral Medicine
Background:
- Stevens-Johnson syndrome (SJS) is a rare, severe mucocutaneous reaction.
- Mycoplasma pneumoniae is a known trigger for SJS.
- Oral manifestations can precede other SJS symptoms.
Purpose of the Study:
- To report a case of Mycoplasma-associated SJS with prominent early oral lesions.
- To highlight the importance of recognizing oral manifestations in SJS diagnosis.
- To emphasize the need for interdisciplinary management of SJS.
Main Methods:
- Case report of a 19-year-old female patient.
- Clinical presentation including oral erosions, blisters, fever, and cough.
- Diagnostic confirmation of Mycoplasma-associated SJS.
- Treatment with steroid pulse therapy and follow-up.
Main Results:
- The patient presented with initial oral lesions followed by skin and ocular involvement.
- Mycoplasma pneumoniae was confirmed as the causative agent.
- Initial response to steroid pulse therapy, followed by relapse and successful re-treatment.
- Oral manifestations served as early indicators of SJS.
Conclusions:
- Oral manifestations can be critical early signs of Stevens-Johnson syndrome.
- Early recognition by oral health professionals is essential for timely diagnosis and intervention.
- Interdisciplinary collaboration improves clinical outcomes for patients with SJS.
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