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Updated: Jan 20, 2026

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Flexible Piezoelectric Sensor for Real-Time Comprehensive Cardiovascular Monitoring.

Nathan Zhang1, Sun Hwa Kwon2, Lin Dong2

  • 1Department of Electrical and Systems Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.

ACS Applied Electronic Materials
|January 19, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a wearable biosensing platform with a piezoelectric nanofibrous sensor and flexible printed circuit board (PCB) for enhanced cardiovascular monitoring. The integrated system reliably captures cardiac signals for comprehensive on-body analysis.

Keywords:
Piezoelectricbiosensorscardiovascular monitoringflexible electronicssignal processing

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Cardiovascular Technology

Background:

  • Wearable cardiovascular monitoring demands sensitive sensors and adaptable electronics for accurate, automated signal processing.
  • Existing solutions often face challenges in signal integrity and on-body integration.

Purpose of the Study:

  • To develop a fully self-contained wearable platform for advanced cardiovascular monitoring.
  • To integrate a piezoelectric nanofibrous sensor with a custom flexible printed circuit board (PCB) for on-body signal amplification and filtering.

Main Methods:

  • Fabrication of a flexible PCB on a polyimide substrate with an ultralow bias current amplifier.
  • Integration of a piezoelectric nanofibrous sensor for high-impedance signal preservation.
  • Electromechanical testing and thermal annealing for performance optimization.
  • System-level evaluation for capturing radial, carotid, and seismocardiogram signals.

Main Results:

  • The flexible PCB successfully amplified and filtered piezoelectric signals on-body.
  • Thermal annealing improved the stability and linearity of the sensor.
  • The platform demonstrated robust performance in capturing multiple cardiovascular signals.
  • Key cardiac parameters were accurately extracted from the monitored signals.

Conclusions:

  • The developed platform offers a practical and comprehensive solution for wearable biosensing.
  • It shows significant potential for continuous, non-invasive cardiovascular health monitoring.
  • The integration of advanced sensor and flexible electronics enables reliable on-body signal processing.