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Related Concept Videos

Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

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Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
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Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
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The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
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Here, a protocol is presented for the metabolic labeling of yeast with 14C-acetic acid, which is coupled with thin layer chromatography for the separation of neutral...
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Updated: Jan 20, 2026

Overview of Lipid Metabolism
01:24

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Endocrine Control of Lipid Metabolism.

Natraj Krishnan1

  • 1Department of Biochemistry, Molecular Biology, Entomology and Plant Pathology, Mississippi State University, Mississippi State, MS, USA. nkrishnan@entomology.msstate.edu.

Advances in Experimental Medicine and Biology
|January 19, 2026
PubMed
Summary

Insect hormones regulate lipid metabolism, impacting energy storage and essential life functions. Studying insect lipid regulation offers insights into human metabolic diseases like diabetes and obesity.

Keywords:
Insulin-like peptidesLipid metabolismLipogenesisLipolysisNeuroendocrine systemPeptidergic hormones

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Area of Science:

  • Insect physiology
  • Endocrinology
  • Metabolic regulation

Background:

  • Lipids are vital for insect energy storage, reproduction, development, and cellular functions.
  • The insect neuroendocrine system governs life activities, including lipid metabolism.
  • Endocrine regulation of lipid metabolism is crucial for understanding insect physiology.

Purpose of the Study:

  • To review current knowledge on endocrine regulation of insect lipid metabolism.
  • To highlight the role of insect peptide hormones in lipogenesis and lipolysis.
  • To explore the utility of insects as models for human metabolic diseases.

Main Methods:

  • Literature review of insect endocrine regulation of lipid metabolism.
  • Identification of key lipogenic and lipolytic hormones in insects.
  • Comparison of insect and mammalian lipid metabolism.

Main Results:

  • Several insect hormones, including insulin-like peptides (ILPs), adipokinetic hormone (AKH), and juvenile hormone (JH), regulate lipid metabolism.
  • Specific neuropeptides stimulate lipogenesis (e.g., DH-PBAN) or lipolysis (e.g., neuropeptide F, ILP6).
  • Insects share physiological similarities with mammals, making them valuable models.

Conclusions:

  • Insect lipid metabolism is intricately regulated by a diverse array of hormones.
  • Understanding insect lipid regulation can provide insights into human metabolic disorders.
  • Insects serve as effective model organisms for studying diseases like diabetes and obesity.