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Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
Published on: January 31, 2020
The Current Landscape of Microbial Biomarkers in Gastrointestinal Disease
Sohn G Kim1, Matthew Y Zhao2, Christine Lam3
1UCLA Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Abstract:
The intestinal microbiome encompasses a complex network of microorganisms that is now recognized to make wide contributions to health and disease but remains incompletely understood. Recent studies provide new insights into distinct roles of the microbiome in specific gastrointestinal diseases and support the possibility of developing new clinical microbial biomarkers for disease diagnosis, risk stratification for disease progression, and prediction of response to therapeutic interventions. Here, we discuss the various potential taxonomic, metabolic, and serologic biomarkers that have been highlighted in recent studies.
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