Related Experiment Video
Updated: Jan 30, 2026
10:11
Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
19.7K
Analysis of Cardiovascular Risk Factors in Patients with Psoriasis: A Cross-Sectional Study
Barbara S Kahlow1, Ana Paula Beckhauser1, Thelma L Skare1
1Department of Medicine, Mackenzie Evangelical School of Medicine Paraná, Curitiba, Paraná, Brazil.
Mediterranean Journal of Rheumatology
|January 29, 2026
Summary
Psoriasis patients show increased atherosclerotic risk, including higher rates of diabetes and hypertension, and elevated carotid intima-media thickness (cIMT). Arthritis did not significantly worsen these cardiovascular risk factors in the study.
Area of Science:
- Cardiovascular Health
- Dermatology
- Rheumatology
Background:
- Psoriasis is linked to increased cardiovascular disease risk.
- Psoriatic arthritis may further elevate this risk.
- Understanding these associations is crucial for patient management.
Purpose of the Study:
- To compare atherosclerotic risk factors and carotid intima-media thickness (cIMT) in psoriasis patients with and without psoriatic arthritis.
- To assess the impact of psoriatic arthritis on cardiovascular risk in psoriasis patients.
Main Methods:
- Retrospective chart review of 127 participants (49 controls, 78 psoriasis patients).
- Collected data on demographics, comorbidities, and treatments.
- Performed laboratory assessments (lipid profile, fasting glucose) and ultrasound-measured cIMT.
Main Results:
- Psoriasis patients had higher frequencies of diabetes and hypertension than controls.
- Psoriasis patients showed significantly elevated cIMT compared to controls (0.68 mm vs. 0.57 mm).
- No significant differences in atherosclerotic risk factors or cIMT were found between psoriasis patients with and without arthritis.
Conclusions:
- Psoriasis patients, irrespective of arthritis, have heightened atherosclerotic risk.
- This study did not demonstrate that psoriatic arthritis exacerbates cardiovascular risk in psoriasis patients.
Related Concept Videos
01:50Cross-Sectional Research
12.5K
In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
12.5K
01:26Factors Affecting the Risk of Infection
13.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.5K
01:24Finding Volume Using Cross-Sectional Area
64
For solids whose cross-sectional areas vary in a predictable way, volume can be determined by integrating these areas along an axis perpendicular to the slices. This approach is particularly useful for polyhedral solids, where classical geometric formulas may not be immediately applicable. A tetrahedron provides a clear example of how cross-sectional integration can be applied to a three-dimensional object with continuously changing geometry.Consider a tetrahedron with height h and a base that...
64
01:26Profile Leveling and Cross Sections
1.6K
Profile leveling and cross-sections are surveying methods used to determine and document terrain elevations for infrastructure projects such as highways, railroads, canals, and pipelines. These methods provide data for earthwork planning and alignment of proposed routes. Profile leveling involves measuring elevations along a fixed line to create a vertical terrain profile. A surveyor sets up a leveling instrument at the benchmark (BM) and records a backsight (BS) to determine the...
1.6K
01:16Spinal Cord: Cross-sectional Anatomy
4.7K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Gray Matter and its Components
Central to the gray matter is...
4.7K
01:29Factors Affecting Protein-Drug Binding: Patient-Related Factors
323
Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
323