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Updated: Feb 10, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
Polyethylene hip resurfacing in patients with lower leg amputations
1Department of Orthopedic Surgery, Swedish Medical Center, Seattle, WA, USA.
Hip resurfacing arthroplasty (HRA) offers a successful alternative for lower extremity amputees experiencing hip issues. This bone-conserving hip surgery demonstrates excellent patient outcomes and implant survivorship, even with common leg length discrepancies.
Area of Science:
- Orthopedic Surgery
- Biomaterials Science
- Rehabilitation Medicine
Background:
- Lower leg amputations increase the risk of early-onset hip osteoarthritis.
- Hip resurfacing arthroplasty (HRA) is a bone-preserving alternative to total hip arthroplasty for amputees.
- Altered gait mechanics in amputees may benefit from HRA's stability and functional advantages.
Purpose of the Study:
- To evaluate the success of HRA as an alternative to total hip replacement in lower extremity amputees.
- To assess functional outcomes and implant survivorship in amputee patients undergoing HRA.
Main Methods:
- Observational study of 39 amputee patients (45 hips) who underwent HRA.
- Patient-reported outcomes measured using HOOS, HHS, MCID, and PASS.
- Long-term follow-up included implant survivorship, complications, and radiographic assessment.
Main Results:
- Mean follow-up of 13 years showed high patient satisfaction (85% PASS) and functional scores (mean HOOS 90, mean HHS 92).
- 92% of patients achieved minimal clinically important difference.
- Leg length discrepancies were common (85%) but did not impact outcomes or survivorship.
Conclusions:
- HRA is a successful and viable surgical option for patients with lower limb amputations requiring hip arthroplasty.
- Leg length differences are frequent in this population but do not negatively affect implant survivorship or patient-reported outcomes.
- HRA provides significant functional benefits and high implant survival rates in amputee patients.
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