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07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
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Definitive embolization of meningiomas: a 20-year updated systematic review
Aaron Brake1, Lane Fry2, Christopher C Young3
1Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA abrakes@icloud.com.
Journal of Neurointerventional Surgery
|February 14, 2026
Summary
Standalone bland embolization for intracranial meningiomas is feasible, offering symptom relief and tumor control. This endovascular therapy may be a viable option for selected patients, even before other treatments.
Area of Science:
- Neurosurgery
- Interventional Radiology
- Oncology
Background:
- Intracranial meningiomas require effective treatment strategies.
- Standalone bland embolization is an emerging endovascular technique.
Purpose of the Study:
- To systematically review outcomes of standalone bland embolization for intracranial meningiomas.
- To summarize clinical, radiographic, and safety data.
Main Methods:
- Systematic PubMed search (inception-December 2025) following PRISMA guidelines.
- Included studies on embolization as primary therapy for intracranial meningiomas.
- Extracted and synthesized data on patient/tumor characteristics, embolic agents, complications, and outcomes.
Main Results:
- 12 studies (30 patients) analyzed; common in older/high-risk patients with convexity/parasagittal tumors.
- Middle meningeal artery embolized in most cases; particles were common embolic agents.
- Mean 37% tumor volume reduction; durable symptomatic improvement reported; low complication rate.
Conclusions:
- Standalone bland embolization is technically feasible for selected intracranial meningiomas.
- It may offer symptom improvement and moderate tumor control, not precluding other therapies.
- Findings provide baseline data for future endovascular therapy trials in meningioma.
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