Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modified-Release Drug Delivery Systems: Rate-Programmed I01:22

Modified-Release Drug Delivery Systems: Rate-Programmed I

35
Rate-programmed drug delivery systems (DDS) are designed to release drugs at specific, controlled rates to maintain consistent therapeutic levels. These systems are categorized based on their release mechanisms, including dissolution-controlled DDS, diffusion-controlled DDS, and combined dissolution-diffusion-controlled DDS.In dissolution-controlled DDS, the release rate depends on the slow dissolution of the drug itself or the surrounding matrix. Drugs with inherently slow dissolution rates,...
35
Modified-Release Drug Delivery Systems: Rate-Programmed II01:19

Modified-Release Drug Delivery Systems: Rate-Programmed II

44
Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...
44
Insulin Formulations: Types and Delivery01:27

Insulin Formulations: Types and Delivery

852
Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
Short-acting insulins are divided into...
852
Modified-Release Drug Delivery Systems: Classification01:23

Modified-Release Drug Delivery Systems: Classification

47
Modified-release drug delivery systems improve drug efficacy and minimize side effects by controlling the rate and location of drug release. These systems fall into three categories: rate-programmed, stimuli-activated, and site-targeted.Rate-programmed systems release drugs at a predetermined rate, maintaining consistent therapeutic levels and reducing fluctuations that could lead to toxicity or subtherapeutic effects. These systems use polymeric matrices, reservoir-based designs, or osmotic...
47

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physics-Informed Neural Network-Enabled Forward Prediction and Inverse Design of Ring Origami.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Spatiotemporal modulation of surface texture for information encoding and object manipulation.

Nature communications·2026
Same author

Rod Origami (RodOri) Spring Metamaterials for Tunable Vibration Control via Tailored Structural Instabilities.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Elastic rod origami (RodOri) for programming static and dynamic mechanical properties.

Science advances·2026
Same author

Safety and Effectiveness of MiniMed™ 780G Advanced Hybrid Closed-Loop Use with Ultrarapid Insulin Lispro-AABC in Pediatric and Adult Type 1 Diabetes.

Diabetes technology & therapeutics·2026
Same author

Swimming With the Omnipod 5 Automated Insulin Delivery System: An Observational Investigation of Swimmers With Type 1 Diabetes in the Omnipod 5 Pivotal Trial.

Diabetes, obesity & metabolism·2026
Same journal

Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning.

Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)·2026
Same journal

RPSLearner: A Novel Approach Based on Random Projection and Deep Stacking Learning for Categorizing Non-Small Cell Lung Cancer.

Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)·2025
Same journal

RanBALL: An Ensemble Machine Learning Framework for Accurate Subtype Identification of Pediatric B-Cell Acute Lymphoblastic Leukemia.

Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)·2025
Same journal

Printed Wearable Sweat Rate Sensor for Continuous <i>in-situ</i> Perspiration Measurement.

Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)·2025
Same journal

Personalized Kirigami Strain Sensors for in vivo Applications.

Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)·2025
Same journal

Minimally Invasive Bowel Cancer Detection through Vibrating Microrobot-Induced Elastography.

Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)·2025
See all related articles

Related Experiment Video

Updated: Feb 24, 2026

A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device
07:55

A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device

Published on: January 26, 2010

12.4K

A Mini-Patch Magnetic Insulin Pump for Enhanced Delivery Resolution and Accuracy.

Qiji Ze1, Shuhao Huang1, Yilong Chang1

  • 1Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA.

Advanced Intelligent Systems (Weinheim an Der Bergstrasse, Germany)
|February 23, 2026
PubMed
Summary
This summary is machine-generated.

A new magnetic insulin pump offers a smaller, more precise alternative to traditional piston-based devices. This innovation improves insulin delivery accuracy and portability for diabetes management.

Keywords:
continuous subcutaneous insulin infusiondrug deliveryinsulin administrationinsulin pumpmagnetic actuation

More Related Videos

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.4K
Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol
08:04

Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol

Published on: November 3, 2023

2.5K

Related Experiment Videos

Last Updated: Feb 24, 2026

A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device
07:55

A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device

Published on: January 26, 2010

12.4K
Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.4K
Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol
08:04

Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol

Published on: November 3, 2023

2.5K

Area of Science:

  • Biomedical Engineering
  • Medical Devices
  • Materials Science

Background:

  • Traditional insulin pumps utilize bulky piston mechanisms, limiting miniaturization and user convenience.
  • Current insulin pumps occupy significant volume due to mechanical transmission systems and insulin reservoirs.

Purpose of the Study:

  • To develop a compact, magnetically actuated insulin pump.
  • To overcome the size and precision limitations of existing piston-based insulin pumps.

Main Methods:

  • A novel magnetic soft actuator directly compresses the insulin chamber, controlled by an electromagnetic field.
  • Elimination of bulky mechanical transmission components in favor of magnetic actuation.

Main Results:

  • The developed magnetic insulin pump is less than one-quarter the size of piston-based pumps.
  • Achieved a delivery resolution of 0.01 μL, significantly higher than the 0.25 μL of piston pumps.
  • Demonstrated superior repeatability and accuracy in various delivery modes compared to commercial pumps.

Conclusions:

  • The miniaturized magnetic insulin pump offers enhanced portability and precision for diabetes management.
  • High-resolution delivery enables the use of concentrated insulins, further reducing device size.
  • This technology promises improved cost-efficiency and user experience for individuals with diabetes.