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Review of Established and Emerging Infectious Diseases in Transfusion Medicine
1Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA; Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.
Abstract:
In 2009 and 2013, the AABB's Transfusion-Transmitted Diseases Committee provided publications on emerging infectious diseases (EIDs) for transfusion medicine. Since that time, they have produced additional EID fact sheets for organisms of potential concern. In this same period, humanity has experienced resurgence of known pathogens, pandemics of novel pathogens, and emergence of nonendemic pathogens in new regions of the world. The 2024 Emerging Infectious Disease special issue provide and in-depth assessment of 72 organisms. In this article, we summarize updated data on organisms of historic concern to the US blood supply, and 2 organism of increased concern to blood safety.
Insights
The AABB
Area of Science:
- Transfusion Medicine
- Infectious Diseases
- Public Health
Background:
- The AABB's Transfusion-Transmitted Diseases Committee has monitored emerging infectious diseases (EIDs) since 2009.
- Global health has seen pathogen resurgences, novel pandemics, and geographic spread of nonendemic pathogens.
- The 2024 Emerging Infectious Disease special issue offers an in-depth assessment of 72 organisms.
Purpose of the Study:
- To summarize updated data on organisms historically relevant to the US blood supply.
- To highlight two organisms of increasing concern for blood safety.
- To provide current information for transfusion medicine professionals.
Main Methods:
- Review and synthesis of updated data on relevant pathogens.
- Assessment of organisms impacting blood safety.
- Analysis of trends in emerging infectious diseases.
Main Results:
- Updated information is provided on historically concerning organisms for the US blood supply.
- Two specific organisms posing increased risks to blood safety are identified.
- The article contributes to the ongoing assessment of EIDs in transfusion medicine.
Conclusions:
- Continuous monitoring of EIDs is crucial for maintaining blood supply safety.
- Transfusion medicine must adapt to evolving infectious disease threats.
- This work supports informed decision-making in blood banking and transfusion practices.
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