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Characterisation of the Novel HLA-B*18:264 Allele by Sequencing-Based Typing
Marine Cargou1, Vincent Elsermans2, Isabelle Top2
1CHU de Bordeaux, Laboratoire D'immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.
A novel Human Leukocyte Antigen B allele, HLA-B*18:264, has been identified. It differs from the known HLA-B*18:01:01:02 allele by a single nucleotide substitution.
Area of Science:
- Immunogenetics
- Molecular Biology
Background:
- Human Leukocyte Antigen (HLA) genes are crucial for immune response.
- Accurate HLA allele identification is vital for transplantation and disease association studies.
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