Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

3.0K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
3.0K
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

14.8K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
14.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Licochalcone A protects against cisplatin-induced acute kidney injury via the modulation of Nrf2/Keap1-mediated ferroptosis and apoptosis.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2026
Same author

The effects of transcranial direct current stimulation on global cognitive function, visuospatial function, and executive function in patients with mild cognitive impairment and Alzheimer's disease: a meta-analysis.

Frontiers in neurology·2026
Same author

Clinical characteristics and prognostic analysis of patients with herpesvirus meningitis/encephalitis based on cerebrospinal fluid mNGS positivity.

Frontiers in neurology·2026
Same author

Effect of Fatty Acid Chain Modification on the Self-Assembly Behavior and Antimicrobial Activity of Antimicrobial Peptides.

Antibiotics (Basel, Switzerland)·2026
Same author

Propensity Score Matching Analysis on Interaction Between Noise Exposure and Gestational Hypertension for Preterm Birth Among Female Workers - 4 PLADs, China, 2024-2025.

China CDC weekly·2026
Same author

A prospective, single-center, quasi-experimental study protocol for evaluating the efficacy of stepwise Yalom group therapy in reducing depressive symptoms and interpersonal problems in Chinese female patients with depressive disorders.

Frontiers in psychology·2026
Same journal

Multifunctional reconfigurable terahertz metasurface based on vanadium dioxide phase transition: achieving broadband absorption and efficient polarization conversion.

Applied optics·2026
Same journal

High-Q-factor electromagnetically induced transparency utilizing quasi-bound states in the continuum in an all-dielectric terahertz metasurface.

Applied optics·2026
Same journal

Automated stitching interferometry for high-precision metrology of X-ray mirrors.

Applied optics·2026
Same journal

Experimental demonstration of an approach to designing a metal-dielectric DBR resonant cavity structure.

Applied optics·2026
Same journal

High-precision wavefront reconstruction from a single-shot interferogram using a physics-driven hybrid feature calibration network.

Applied optics·2026
Same journal

Ultra-high-Q Fano resonance based on coupled topological corner states in Kagome photonic crystals.

Applied optics·2026
See all related articles

Related Experiment Video

Updated: Mar 19, 2026

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
08:41

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

Published on: August 16, 2012

12.1K

Particle swarm optimization-driven tomographic metalens for controllable super-resolution focusing.

Hongyan Yang, Minjie Zhang, Weijie Chen

    Applied Optics
    |March 17, 2026
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel metalens for tomographic imaging, overcoming limitations of traditional methods. It achieves high-resolution, broadband imaging with tunable focal length using particle swarm optimization (PSO).

    More Related Videos

    Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging
    10:01

    Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging

    Published on: September 8, 2017

    8.3K
    Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform
    06:25

    Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

    Published on: February 12, 2014

    8.9K

    Related Experiment Videos

    Last Updated: Mar 19, 2026

    Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
    08:41

    Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

    Published on: August 16, 2012

    12.1K
    Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging
    10:01

    Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging

    Published on: September 8, 2017

    8.3K
    Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform
    06:25

    Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

    Published on: February 12, 2014

    8.9K

    Area of Science:

    • Photonics
    • Computational Imaging
    • Optical Metrology

    Background:

    • Traditional confocal microtomography suffers from complex setups, low integration, and poor stability.
    • Limitations hinder advanced applications in high-resolution imaging and miniaturization.

    Purpose of the Study:

    • To develop an integrated tomographic focusing metalens solution.
    • To overcome the limitations of conventional microtomography techniques.
    • To achieve broadband, high-resolution spectral performance in visible wavelengths.

    Main Methods:

    • Utilizing a metalens with particle swarm optimization (PSO) algorithm for phase compensation.
    • Implementing PSO for controllable focal length and tunable focal point separation.
    • Simulating tomographic scanning depth, numerical aperture (NA), and full width at half-maximum (FWHM).

    Main Results:

    • Achieved a tomographic scanning depth of 12.65 µm within the 0.48-0.68 µm visible wavelength range.
    • Demonstrated tunable focal length and precise control over focal point separation via PSO.
    • Attained a maximum NA of 0.61, with FWHM near the diffraction limit, and ultra-high resolution at 0.60 µm.

    Conclusions:

    • The proposed metalens offers a stable, integrated solution for tomographic imaging.
    • This technology enables controllable, broadband, high-resolution imaging with potential quantum effects.
    • Presents a novel paradigm for miniaturized computational photonics in imaging.