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Revolutionizing Sun Protection: Emerging Nanotechnologies Shaping the Future of Sunscreens
Millena de S Afonso1, Pamella M de Souza2, Adriany L Dos Santos2
1Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.
ACS Pharmacology & Translational Science
|March 19, 2026
Summary
Nanotechnology enhances sunscreen formulations, improving UV protection and performance. Further safety studies are needed to ensure no adverse effects from these advanced sunscreens.
Area of Science:
- Pharmaceutical Sciences
- Cosmetic Science
- Materials Science
Background:
- Sun protection is a major public health concern due to rising skin disease rates linked to UV exposure.
- Nanosystems in sunscreens offer innovative solutions in pharmaceutical and cosmetic applications.
- Ultraviolet (UV) radiation exposure necessitates effective sun protection strategies.
Purpose of the Study:
- To map and characterize scientific studies on nanotechnology applications in sunscreen formulations.
- To evaluate the effectiveness and safety of nanotechnology-based sunscreens.
- To identify trends in the development of advanced sunscreen formulations.
Main Methods:
- Comprehensive literature searches were conducted across major scientific databases (PubMed, Embase, Lilacs, Scopus, Web of Science, Google Scholar).
- Fifty-four studies focusing on the development and evaluation of nanotechnology-associated sunscreen formulations were included.
- Systematic review and categorization of existing research on nanosystems in sunscreens.
Main Results:
- Nanotechnology significantly improves pharmaceutical sunscreen formulations, enhancing performance and UV filter efficacy.
- Nanosystems offer advanced active delivery systems for developing superior sunscreen products.
- The integration of nanotechnology leads to more effective UV protection.
Conclusions:
- Nanotechnology is a key strategy for developing advanced and effective sunscreen formulations.
- While promising, further research, particularly on safety and systemic absorption, is crucial.
- Continued investigation into nanotechnology's role in sunscreens is essential for public health advancements.

