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Published on: October 24, 2019
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Bibliometric Analysis of Randomized Clinical Trials in the Philippines
Ian Theodore G Cabaluna1,2, Sarah F Sevilla3, Arianna Maever L Amit4,5
1Institute of Clinical Epidemiology, National Institutes of Health, University of the Philippines Manila, Manila, Philippines.
Acta Medica Philippina
|March 27, 2026
Summary
The Philippines shows a growing number of published randomized controlled trials (RCTs), with infectious diseases being a key research area. Strengthening research platforms and collaborations can further boost global contributions.
Area of Science:
- Clinical Research
- Bibliometrics
- Evidence-Based Healthcare
Background:
- Randomized controlled trials (RCTs) are crucial for evaluating health interventions.
- The Philippines has historically had limited output in global RCTs.
- Assessing RCT trends in the Philippines is vital for understanding research capacity.
Purpose of the Study:
- To analyze the trends, characteristics, and impact of RCTs conducted in the Philippines.
- To identify publication patterns, funding, study designs, and institutional contributions.
- To evaluate the growth and identify areas for improvement in Philippine clinical research.
Main Methods:
- Systematic literature search of Medline (PubMed), EMBASE, and Acta Medica Philippina (1990-2022).
- Screening and analysis of eligible RCTs based on predefined criteria.
- Descriptive statistics to summarize publication trends, funding, study designs, research settings, and institutional output.
Main Results:
- 391 RCTs identified, showing an increasing publication trend.
- Most studies published internationally, primarily funded by pharmaceutical companies.
- Infectious diseases (especially vaccine-preventable) led research areas; hospitals were common settings.
- Leading institutions included University of the Philippines Manila and Research Institute for Tropical Medicine.
Conclusions:
- The rise in RCT publications indicates enhanced research capacity in the Philippines.
- Further development of national dissemination platforms is recommended.
- Fostering regional collaborations is key to increasing global impact.
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