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Updated: Mar 30, 2026

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
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Open and Endoscopic Open-Assisted Repair of Anterior Skull Base Defects.
Somtochi I Okafor1, Mathew Geltzeiler2
1Department Otolaryngology-Head & Neck Surgery, Oregon Health & Science University, OHSU Oregon Sinus Center, Portland, OR, USA.
Otolaryngologic Clinics of North America
|March 28, 2026
Summary
Open and combined surgical approaches remain crucial for complex frontal sinus cases, especially with extensive tumors or prior treatments. These methods integrate open craniotomy with endoscopic techniques for effective anterior skull base defect repair.
Area of Science:
- Neurosurgery
- Otolaryngology
- Skull Base Surgery
Background:
- Endoscopic surgery is increasingly preferred for frontal sinus procedures.
- However, open and combined approaches are still necessary in specific complex scenarios.
Purpose of the Study:
- To highlight the continued relevance of open and combined surgical techniques for frontal sinus pathologies.
- To describe the indications and utility of combined approaches in anterior skull base reconstruction.
Main Methods:
- Review of complex frontal sinus cases where open or combined approaches were utilized.
- Description of combined open craniotomy and endoscopic techniques for anterior skull base defect repair.
Main Results:
- Open and combined approaches are indicated for extensive tumors, visualization challenges, and cases with prior surgery or radiation.
- Combined techniques effectively repair cerebrospinal fluid leaks while preserving frontal sinus function.
Conclusions:
- Open and combined surgical strategies are indispensable for managing challenging frontal sinus conditions.
- These integrated approaches offer solutions for complex anterior skull base defects and cerebrospinal fluid leaks.
Keywords:
Anterior skull base surgeryCSF rhinorrheaCranializationOpen skull base surgeryOsteoplastic flapPericranial flapSkull base malignancy
