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Updated: Mar 31, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Volumetric changes associated with immediate implant placement and Bio-Oss collagen
Harsh Ranjan1, Shamna Alathankandy Vaniyanveetti2, Srilekha Pulivarthi3
1Department of Dental and Surgery, Oral and Maxillofacial Surgery, Consultant at Narayan Hospital and Ambika Hospital, Patna, Bihar, India.
None:
Volumetric changes associated with immediate implant placement and Bio-Oss collagen is observed. Hence, Thirty patients requiring single-tooth extraction and immediate implant placement in the anterior maxilla were randomly allocated into two groups: Group A (n=15) received immediate implants with Bio-Oss Collagen filling the gap and Group B (n=15) received immediate implants without grafting. Cone-beam computed tomography (CBCT) scans were obtained immediately post-operatively and at six months. Volumetric measurements were performed using three-dimensional image analysis software. Statistical analysis included paired and independent t-tests. Bio-Oss Collagen significantly reduced volumetric bone resorption following immediate implant placement, demonstrating superior preservation of peri-implant hard tissue dimensions compared to non-grafted sites.
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