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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Inflammatory Response I: Vascular and Cellular01:30

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The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
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Inflammatory Response01:28

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An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

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The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
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Updated: Apr 10, 2026

Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis
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An Update on Inflammatory Dermatopathology.

Sarah A Abdel-Mageed1, Karolyn A Wanat1

  • 1Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI, USA.

Dermatologic Clinics
|April 8, 2026
PubMed
Summary
This summary is machine-generated.

This review covers rare inflammatory skin diseases, focusing on clinical and histopathologic features of postradiation morphea, infectious dermatoses, vasculitis, annular erythemas, and neutrophilic dermatoses.

Keywords:
Annular erythemaNeutrophilic dermatosesPost-radiation morpheaReactive dermatosesVasculitisVasculopathy

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Inflammatory dermatopathology includes diverse nonneoplastic skin conditions.
  • Rare and emerging diseases present diagnostic challenges.

Purpose of the Study:

  • To summarize clinical and histopathologic findings of rare and emerging inflammatory dermatologic diseases.
  • To categorize these conditions for better understanding.

Main Methods:

  • Literature review and synthesis of existing data.
  • Focus on clinical presentation and histopathologic characteristics.

Main Results:

  • Detailed discussion of postradiation morphea.
  • Overview of reactive infectious dermatoses.
  • Analysis of vasculopathies and vasculitides.
  • Exploration of annular erythemas.
  • Examination of neutrophilic dermatoses.

Conclusions:

  • Understanding these rare conditions is crucial for accurate diagnosis.
  • Histopathology plays a key role in identifying these inflammatory dermatoses.