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Updated: Apr 15, 2026

Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
Published on: May 23, 2014
[Clear cell adenocarcinoma from cicatricial endometriosis]
Josefine Reinhardt Nielsen1, Catrine Carlstein2, Jacob Brink Laursen2
1Gynækologisk-Obstetrisk Afdeling, Københavns Universitetshospital - Amager og Hvidovre Hospital.
Abstract:
Clear cell adenocarcinoma arising from abdominal wall endometriosis (AWE) is extremely rare. We report a case of a 60-year-old woman with a history of cesarean section and surgically treated AWE. Decades after initial resection, she developed recurrent pain and a palpable mass. Initial evaluation raised suspicion for other conditions, leading to a diagnostic delay. Subsequent workup confirmed clear cell adenocarcinoma. She underwent radical surgery and was diagnosed with FIGO stage IV B disease. The case highlights the malignant potential of endometriosis and the need for clinical vigilance.
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