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Updated: Apr 15, 2026

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
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Performance Evaluation of the Newly Developed H-120 HbA1c Analyzer.

Anping Xu, Hui Yu, Rui Ji

    Clinical Laboratory
    |April 14, 2026
    PubMed
    Summary

    The new Mindray H-120 Hemoglobin A1c (HbA1c) analyzer demonstrates excellent precision and accuracy. Its robust performance and variant detection make it ideal for clinical laboratory use.

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    Area of Science:

    • Clinical Chemistry
    • Analytical Performance Evaluation
    • Chromatography Techniques

    Background:

    • Evaluation of novel diagnostic instrumentation is crucial for advancing clinical laboratory efficiency.
    • The Mindray H-120 is a new Hemoglobin A1c (HbA1c) analyzer utilizing ion-exchange high-performance liquid chromatography (HPLC).

    Purpose of the Study:

    • To assess the analytical performance of the Mindray H-120 HbA1c analyzer.
    • To compare its performance against established analyzers and evaluate its capability in handling hemoglobin variants.

    Main Methods:

    • Assessed precision, accuracy, and linearity of the H-120 in standard and variant modes.
    • Evaluated interference from hemoglobin variants and compared results with D100 and Capillarys 3 TERA analyzers.

    Main Results:

    • The H-120 exhibited excellent precision (CV ≤ 0.5%) and accuracy (bias ± 2.0% vs. IFCC controls).
    • Demonstrated strong linearity (3.0%-20.1% HbA1c) and perfect agreement between H-120 modes (r=1.000).
    • Showed high consistency with other analyzers (r ≥ 0.998) and detected 9/10 common Hb variants, with 83.8% not affecting HbA1c measurements.

    Conclusions:

    • The Mindray H-120 analyzer provides outstanding fundamental performance.
    • Features robust variant detection and user-friendly operation, meeting clinical laboratory needs.