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Updated: May 16, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
08:49

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Published on: January 22, 2019

Modulation of the mevalonate pathway by TCR engagement regulates T follicular helper cell generation in homeostasis

Lai Wang1, Jiao Jiang2, Haoyuan Yin1

  • 1Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China; Key Laboratory of Basic and Translational Research on Immune-Mediated Skin Diseases, Chinese Academy of Medical Sciences, Nanjing, Jiangsu 210042, China; Jiangsu Provincial Key Laboratory of Dermatology, Nanjing, Jiangsu 210042, China.

Immunity
|May 14, 2026
PubMed

Keywords:
CXCR5RAB35T follicular helper cellsautoimmune diseasesgeranylgeranyl diphosphatepitavastatinsurface protein expression

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