Linking vitamin D levels with recurrent wheeze among Indian children

Vitamin D deficiency (< 20 ng/mL) in children aged 1-5 is linked to higher recurrent wheeze risk via immune dysregulation, but supplementation trials show mixed results. Therefore, it is of interest to assess the association between vitamin D deficiency in children and recurrent wheeze in children aged 1 to 5 years. The total sample size was 80 and the data regarding the patient demographic variables, history of symptoms and allergy, GERD-related recurrent aspiration, history of nebulization, hospital stay etc., were collected using standard Questionnaire. The mean vitamin D level in the study participants was 27.18 ± 7.86 ng/mL and out of 80 cases, the majority, 45% of patients, had WALRI, followed by 27.5% of patients who had pneumonia. Among patients with five wheeze episodes per year, maximum patients 71.4% showed vitamin D levels 11 to 30ng/ml. Thus, Vitamin D supplementation programmes on a national scale help reduce the epidemic of vitamin D insufficiency.