Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discovery of a Thermostable Nigerose Phosphorylase for the Efficient Chemoenzymatic Radiosynthesis of a <i>S. aureus</i>-Targeted <sup>18</sup>F-Disaccharide.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Evaluation of radiation damage effects of low-energy Auger and conversion electrons emitted by <sup>134</sup>Ce decay using a Monte Carlo method.

Scientific reports·2026
Same author

Tumor response and tolerability under fractionated x-ray irradiation in a mouse xenograft model.

Physics in medicine and biology·2026
Same author

A Prodrug Strategy to Conditionally Trap Therapeutic Payloads for Improved Tumor Retention.

ACS central science·2026
Same author

Pair production tomography enables imaging of MeV-scale gamma-emitting theranostic radionuclides.

Research square·2026
Same author

Mitochondrial Imaging Detects Early Cardiac Changes Following Cancer Immunotherapy.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
Same journal

Future Challenges of Molecular Imaging in Oncology.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
Same journal

Clinical Applications of Theranostics.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
Same journal

Internal Radiation Therapy.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
Same journal

The Role of Molecular Imaging in Ion Beam Therapy.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
Same journal

Molecular Imaging in Photon Radiotherapy.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
Same journal

Advancements in Intraoperative Imaging for Enhanced Surgical Precision.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
See all related articles

Related Experiment Video

Updated: May 19, 2026

Cerenkov Luminescence Imaging (CLI) for Cancer Therapy Monitoring
08:45

Cerenkov Luminescence Imaging (CLI) for Cancer Therapy Monitoring

Published on: November 13, 2012

Pre-clinical SPECT and SPECT-CT in Oncology.

Youngho Seo1, Elena M Zannoni2

  • 1Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA. youngho.seo@ucsf.edu.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|May 18, 2026
PubMed
Summary
This summary is machine-generated.

Molecular imaging with single photon emission computed tomography (SPECT) offers insights into cancer development and spread. Advances in SPECT and radiopharmaceuticals enhance sensitivity for drug discovery and treatment monitoring in oncology.

Keywords:
Alpha particlesBeta particlesCancer ImagingCollimatorPreclinical SPECTPreclinical SPECT/CTPreclinical SPECT/MRIQuantitative SPECTRadiation detectionRadiation dosimetryTheranostics

More Related Videos

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
07:36

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

Published on: May 16, 2020

Related Experiment Videos

Last Updated: May 19, 2026

Cerenkov Luminescence Imaging (CLI) for Cancer Therapy Monitoring
08:45

Cerenkov Luminescence Imaging (CLI) for Cancer Therapy Monitoring

Published on: November 13, 2012

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
07:36

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

Published on: May 16, 2020

Area of Science:

  • Nuclear medicine
  • Molecular imaging
  • Oncology

Background:

  • Molecular imaging provides spatial and temporal insights into carcinogenesis and malignant spread.
  • Single photon emission computed tomography (SPECT) is a nuclear imaging technique suitable for studying these processes in vivo.
  • SPECT is valuable for identifying drug candidates and characterizing their effects in cancer research.

Purpose of the Study:

  • To highlight advances in small-animal SPECT, SPECT-CT, and SPECT-MR systems.
  • To discuss the evolution of radiopharmaceuticals for SPECT imaging.
  • To explore applications in oncology and new research areas.

Main Methods:

  • Utilizing advanced small-animal SPECT, SPECT-CT, and SPECT-MR systems.
  • Employing a variety of radiopharmaceuticals for SPECT imaging.
  • Leveraging quantitative molecular imaging capabilities.

Main Results:

  • Enhanced sensitivity and quantitative capabilities in molecular imaging.
  • Improved characterization of anti-tumor action and potential adverse effects of drug candidates.
  • Demonstration of novel applications in oncology research.

Conclusions:

  • SPECT technology and radiopharmaceuticals have significantly advanced molecular imaging in oncology.
  • These advancements enable unprecedented sensitivity and quantitative analysis for cancer research.
  • Future exploration of new applications holds promise for further understanding and treatment of cancer.