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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

Non-FDG PET/CT.

Priscilla Guglielmo1,2, Stefano Fanti3, Laura Evangelista4,5

  • 1Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy. priscilla.guglielmo@gavazzeni.it.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
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Positron emission tomography (PET) is vital in cancer imaging. While [18F]FDG PET is standard, new tracers are emerging to better understand cancer biology and improve oncological imaging.

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Area of Science:

  • Oncology
  • Molecular Imaging
  • Radiochemistry

Background:

  • Positron emission tomography (PET) is primarily used in clinical oncology.
  • [18F]FDG remains the most common PET radiopharmaceutical for cancer imaging.
  • Advances in understanding cancer biology have led to the development of new PET tracers.

Purpose of the Study:

  • To provide an overview of select non-FDG PET tracers.
  • To highlight the integration of these tracers into clinical workflows.
  • To discuss their contributions to oncological imaging.

Main Methods:

  • Review of current literature on non-FDG PET tracers.
  • Analysis of clinical applications and workflow integration.
  • Discussion of advancements in molecular imaging for oncology.

Main Results:

  • Several novel non-FDG PET tracers have been developed.
  • These tracers offer insights into specific metabolic and pathogenic pathways in cancer.
  • Integration into clinical practice is expanding.

Conclusions:

  • Non-FDG PET tracers represent a significant advancement in oncological imaging.
  • They complement [18F]FDG PET by providing more specific diagnostic information.
  • Continued innovation in PET tracer development is crucial for personalized cancer care.