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Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
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Published on: October 2, 2014

Letter Regarding: "The Value of Radiation Therapy in Retroperitoneal Sarcoma: In Response to Papai et al."

Cole Friedes1, Steven Feigenberg1, Daniel Lefler2

  • 1Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

The Journal of Surgical Research
|May 26, 2026
PubMed
Summary

No abstract available in PubMed .

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

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