Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From the Pain Matrix to Functional Networks: A Narrative Review of Chronic Pain Mechanisms Across Adult and Pediatric Populations with Emerging AI Perspectives.

Brain sciences·2026
Same author

High Fidelity Simulations to Improve Pediatric Airway Management: A Narrative Review.

Healthcare (Basel, Switzerland)·2026
Same author

Measurement Instruments Used to Assess Caregiver Burden in Informal Caregivers of Adult Cancer Patients: A Systematic Review.

Nursing reports (Pavia, Italy)·2026
Same author

Artificial Intelligence in Medicine: Basic Knowledge, Applications, Ethics and Perspectives.

Journal of evaluation in clinical practice·2026
Same author

Oligometastatic versus polymetastatic colon cancer: functional and genomic determinants of divergent metastatic trajectories.

Exploration of targeted anti-tumor therapy·2026
Same author

Feasibility Assessment of Telehealth-Based Cancer Pain Management Through Machine Learning: A Prospective Clinical Study.

Pain research & management·2026
Same journal

Endovascular Embolization of Pulmonary Sequestration in Children with Contraindications to Surgery: A Two-Centre Experience with Long-Term Follow-Up.

Children (Basel, Switzerland)·2026
Same journal

Postsynaptic Congenital Myasthenic Syndrome Mimicking Limb-Girdle Muscular Dystrophy Associated with an Alternatively Spliced Exon in CHRNB1: A Case Report and Literature Review.

Children (Basel, Switzerland)·2026
Same journal

Effectiveness of Buzzy BEE in Reducing Pain Perception During Inferior Alveolar Nerve Block in Children: A Split-Mouth Crossover Study.

Children (Basel, Switzerland)·2026
Same journal

Robot-Assisted Versus Laparoscopic Ureteroureterostomy for Duplicated Kidney Malformations in Infants: A Comparative Cohort Study.

Children (Basel, Switzerland)·2026
Same journal

Diagnostic Performance of Inflammatory Biomarkers in Pediatric Acute Appendicitis.

Children (Basel, Switzerland)·2026
Same journal

A Qualitative Study of Participant Feedback on an Acceptance and Commitment Therapy Group-Based Intervention for Parents of Youth with Anxiety Disorders.

Children (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: May 28, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Multidisciplinary Strategies for Tailored Anesthesia Management in Children Undergoing Radiotherapy.

Salvatore Palmese1, Renato Gammaldi1, Alessandro Vittori2

  • 1Department of Anesthesia and Intensive Care, AOU "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.

Children (Basel, Switzerland)
|May 27, 2026
PubMed
Summary
This summary is machine-generated.

Pediatric radiotherapy requires careful anesthetic management due to repeated sedation needs. This review covers anesthetic strategies, safety, and multidisciplinary care for children undergoing radiation therapy.

Keywords:
anesthesiadeep sedationmidazolammultidisciplinary carenon-operating room anesthesia (NORA)pediatric radiotherapypropofol

More Related Videos

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
15:18

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Published on: July 30, 2009

Related Experiment Videos

Last Updated: May 28, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
15:18

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Published on: July 30, 2009

Area of Science:

  • Pediatric Anesthesiology
  • Radiation Oncology
  • Pediatric Oncology

Background:

  • Radiotherapy is vital for pediatric cancers but presents anesthetic challenges in children.
  • Children often need repeated sedation or general anesthesia for immobility and to reduce distress during lengthy treatments.

Purpose of the Study:

  • To review current evidence on anesthetic strategies for pediatric radiotherapy.
  • To focus on clinical indications, pharmacology, safety, and organizational aspects of pediatric anesthesia during radiation therapy.

Main Methods:

  • Narrative review of current evidence.
  • Discussion of sedation and anesthesia techniques in non-operating room anesthesia (NORA) settings.
  • Examination of pharmacological agents like midazolam, propofol, ketamine, and dexmedetomidine.

Main Results:

  • Anesthetic management requires attention to cumulative effects, airway challenges in remote settings, and potential complications.
  • Individualized, protocol-driven management, rapid recovery, and continuous monitoring are highlighted.
  • Non-pharmacological and audiovisual techniques may reduce anesthesia needs.

Conclusions:

  • A multidisciplinary approach is essential for optimizing safety, adherence, and care quality.
  • Tailored anesthetic management with standardized protocols and pediatric expertise is crucial for balancing efficacy and safety.