Related Experiment Video
Updated: Jun 11, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Pediatric hematology: which conditions and how are they managed?]
1Service d'immuno-hématologie pédiatrique, hôpital Robert-Debré, AP-HP, 48 boulevard Sérurier, 75019 Paris, France.
Abstract:
The Pediatric Immunology and Hematology Unit at Robert-Debré Hospital treats a wide range of malignant and non-malignant disorders of the blood and the immune system. Significant advances in medical research enable us to offer patients cutting-edge therapies, ranging from established standard-of-care treatments that are regularly optimized to the most innovative immunotherapies. This care also involves comprehensive multidisciplinary support involving various medical professionals (pediatricians, biologists, pharmacists, geneticists, radiologists, etc.) and paramedical staff (nurses providing routine care and coordination, psychologists, teachers, secretaries, clinical research associates, social workers, etc.) to ensure full alignment with the treatment plan.
Related Concept Videos
Disorders of Erythrocytes
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Distribution
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Overview of Hematopoiesis
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
