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Oncofertility in Pediatric and Adolescent Patients: Current Practice and Future Directions
Rohini Chakravarthy1, Monica M Laronda2, Sara Zarnegar-Lumley3
1Division of Hematology and Oncology, Department of Pediatrics, Comer Children's Hospital, University of Chicago School of Medicine, University of Chicago, 5837 South Maryland Avenue Wyler C-425B, Chicago, IL 60637, USA.
Childhood cancer survivors prioritize fertility and reproductive health. Continued research and advocacy are crucial to overcome barriers and ensure access to fertility preservation options for all patients.
Area of Science:
- Oncology
- Reproductive Medicine
- Oncofertility
Background:
- Reproductive health and fertility are vital for childhood cancer survivors' quality of life.
- Oncofertility has advanced significantly, improving fertility preservation options.
- Despite progress, barriers to fertility care persist, and long-term outcomes are often unknown.
Purpose of the Study:
- To highlight the importance of fertility considerations in cancer survivorship.
- To review advancements in oncofertility and remaining challenges.
- To advocate for continued research and equitable access to reproductive health services.
Main Methods:
- Literature review on oncofertility advancements.
- Analysis of current barriers in fertility preservation.
- Discussion of the need for ongoing research and advocacy.
Main Results:
- Oncofertility has developed risk stratification and multidisciplinary care models.
- Fertility preservation is increasingly prioritized for cancer patients.
- Significant barriers remain, impacting long-term success and access.
Conclusions:
- Ensuring access to reproductive health care is essential for cancer survivors.
- Further research is needed to understand long-term fertility preservation success rates.
- Advocacy efforts must continue to address existing barriers and promote comprehensive survivorship care.
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