Related Experiment Video
Updated: Jun 24, 2026

Preparation of Cross-Linked Sodium Alginate Microspheres with Different Metal Ions Using the Microfluidic Electrospray Technology
Published on: June 7, 2024
Emulsion-Derived Production of Drug-Loaded Microgranules as an Alternative to Spray Drying
Soumyajyoti Chatterjee1, Anisha Kabir2, Vedant Goankar3
1Polymer Engineering and Colloid Science Lab, Department of Chemical Engineering, Indian Institute of Technology Madras, Chennai 600036, India.
None:
Microgranules are a class of synthetic functional materials designed for the delivery of active compounds in diverse sectors, including pharmaceuticals, agriculture, food, and cosmetics. In this work, we present a scalable emulsion-based method for fabricating microgranules with robust mechanical and structural properties. We successfully encapsulate an antidiabetic drug within these microgranules and analyze drug loading using microscopy, spectroscopy, and thermal techniques. In vitro drug release profiles are obtained and modeled to understand the underlying release mechanism. Biocompatibility assessments using the MTT assay confirm the excellent cytocompatibility of drug-loaded microgranules. Overall, the emulsion-based approach offers a versatile and scalable platform for the encapsulation and controlled release of therapeutic agents and other functional molecules.
Related Concept Videos
Factors Affecting Dissolution: Particle Size and Effective Surface Area
Factors Influencing Drug Absorption: Pharmaceutical Parameters
In Vitro Drug Dissolution: Alternative Methods
Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence
Modified-Release Drug Delivery Systems: Rate-Programmed II
