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Updated: Jun 26, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
Orthostatics Are Useful in Assessing Volume Status: Myth or Reality?
1Northwell, New Hyde Park, NY, USA; Department of Emergency Medicine, Staten Island University, Staten Island, NY, USA.
Abstract:
Orthostatic vital signs (OVS) have long been a routine part of volume assessment in the emergency department. However, recent evidence demonstrates poor sensitivity and specificity for detecting moderate hypovolemia, with high variability across patient populations. This article reviews the physiologic basis, diagnostic limitations, and alternative methods for assessing intravascular volume, including point-of-care ultrasound and dynamic indices. Ultimately, OVS remain a simple bedside adjunct but should be interpreted cautiously and within the broader clinical context.
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