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Updated: Jun 29, 2026

Ammonia Synthesis at Low Pressure
Published on: August 23, 2017
In Situ Production of Phosgene: Utilization in Urea Synthesis
Dan-Ting Wei1, Bin-Xuan Zou1, Li-Gang Kou1
1Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry & Materials Science, School of Foreign Languages, Northwest University; Xi'an 710127, China.
Abstract:
Phosgene, as a crucial chemical, is used to produce polymers, agrochemicals, and pharmaceuticals. Herein, we report a mild iron-catalyzed in situ conversion of CCl4 to phosgene, applied to the synthesis of various ureas. Using Fe(acac)3/CCl4 to replace dangerous phosgene offers significant advantages in terms of its safety and easy operation. Given the broad utility of phosgene and the importance of ureas in drugs and functional materials, this method, as a convenient and adaptable approach, holds promise for academic and industrial applications.
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