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Healthcare Agencies I

Healthcare Agencies I

Healthcare agencies provide healthcare services to people. In the United States, voluntary agencies are often non-profit centers sponsored by donations, grants, or fundraisers. One such organization is Meals on Wheels, which provides meals to the elderly and homebound. The American Heart Association and the American Lung Association are other non-profit community organizations. Doctors and nurses are frequently active members of these organizations, which offer health checks and educational...

Healthcare Agencies II

Healthcare Agencies II

There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources, and lay...

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Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

Infectious Diseases and Their Occurrence

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Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...

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Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...

Coronavirus

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Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...

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Updated: Jul 3, 2026

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic

Published on: November 7, 2020

MediLabSecure: A One Health Network Facing the COVID-19 Pandemic DVM.

Guillain Mikaty¹, Wasfi Fares¹, Rita Feghali¹

¹Guillain Mikaty, PhD, is a Microbiologist, and Jean-Claude Manuguerra, DVM, PhD, is Head of Unit; both in the Environment and Infectious Risk Research Unit - Laboratory for Urgent Response to Biological Threats (ERI-CIBU), Institut Pasteur, Université de Paris Cité, Paris, France. Wasfi Fares, PhD, is a Virologist, Laboratory of Clinical Virology, Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia. Rita Feghali, MD, PhD, is Head, Laboratory Department, Rafic Hariri University Hospital (RHUH), Bir Hassan, Jnah, Beirut, Lebanon; and [title], Lebanese American University School of Medicine, Beirut, Lebanon. Sylvia Karam is a Technician, Laboratory Department, RHUH, Bir Hassan, Jnah, Beirut, Lebanon. Elisa Pérez-Ramírez, PhD, Jovita Fernández-Pinero, PhD, and Miguel Angel Jiménez-Clavero, PhD, are Virologists, Centro de Investigación en Sanidad Animal (CISA-INIA), CSIC, Valdeolmos, Spain. Oliver Donoso Mantke, PhD, and Elaine McCulloch, PhD, are Microbiologists; both at Quality Control for Molecular Diagnostics, Glasgow, Scotland. Olfert Landt, PhD, is a Biologist, TIBMolbiol Syntheselabor GmbH, Berlin, Germany. Vincent Robert, PhD, is a Medical Entomologist, MIVEGEC unit, Centre National de Recherche Scientifique, Institut de Recherche pour le Développement, Université de Montpellier, Montpellier, France. Maria Grazia Dente, PhD, and Silvia Declich, PhD, are Epidemiologists, National Centre for Global Health, Istituto Superiore di Sanità, Rome, Italy. Guy Hendrickx, PhD, is [job title], Research Department, AVIA-GIS, Zoersel, Belgium. Vanessa Lagal, PhD, Serena Battaglia, PhD, and Nada Essawy are Project Managers; and Maud Seguy, PhD, is Head; all in Institut Pasteur, Université Paris Cité, Department of International Affairs, Paris, France.

Health Security

|July 2, 2026

Summary

This summary is machine-generated.

The MediLabSecure project enhanced diagnostic and sequencing capabilities for zoonotic viruses, significantly aiding early COVID-19 detection across 15 countries. This highlights the value of international One Health initiatives in global health security.

Keywords:

COVID-19 Capacity building Diagnostics External quality assessment (EQA)MediLabSecure One Health Network SARS-CoV-2

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Area of Science:

Global Health Security
Infectious Disease Surveillance
One Health Approach

Background:

Existing surveillance systems and preparedness efforts were in place prior to the COVID-19 pandemic.
The rapid identification and sequencing of SARS-CoV-2 demonstrated improvements in global monitoring systems.
Developing sensitive diagnostic tools for novel viruses like SARS-CoV-2 presented an immediate challenge.

Purpose of the Study:

To assess the role of the MediLabSecure project in supporting diagnostic and sequencing capacities for SARS-CoV-2.
To advocate for the importance of One Health principles and international capacity-building programs.
To demonstrate the effectiveness of multisectoral collaboration in combating emerging infectious diseases.

Main Methods:

MediLabSecure provided protocols, reagents, and positive controls for RT-qPCR diagnostics to laboratories in 21 countries.
The project shared sequencing protocols and offered training for virus characterization.
A One Health approach integrated public health and veterinary laboratories.

Main Results:

MediLabSecure's support was critical for the initial detection of SARS-CoV-2 cases in 15 network countries.
Over 23,000 diagnostic reactions were supported across 21 countries.
The collaborative One Health approach proved beneficial for both public health and veterinary sectors.

Conclusions:

International capacity-building projects like MediLabSecure are essential for a multisectoral response to emerging infectious diseases.
The One Health approach enhances the efficiency and resilience of public health systems.
Sustained investment in preparedness and international cooperation is vital for global health security.