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Related Experiment Video

Updated: Jul 4, 2026

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
08:42

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

Published on: July 3, 2020

Celastrol Attenuates Fgf23 Expression in Osteoblasts by Inhibiting STAT3 Activation

Jiawei Cao1, Yuewen Tang1,2, Feng Wan1,3

  • 1Department of Nephrology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.

Endocrine, Metabolic & Immune Disorders Drug Targets
|July 3, 2026
PubMed
Summary

No abstract available in PubMed .

Keywords:
CKDExtracellular phosphateFGF23STAT3celastrolosteoblasts

Related Experiment Videos

Last Updated: Jul 4, 2026

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
08:42

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

Published on: July 3, 2020

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TGF - β Signaling Pathway01:16

TGF - β Signaling Pathway

The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors are of three kinds RI, RII, and RIII. The RI...

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