[Sarcoidosis]

Sarcoidosis is a granulomatous disease that can affect any organ but almost always involves the lungs (>90%). Extrapulmonary involvement is frequent, particularly affecting the skin, eyes, and lymph nodes, while cardiac, kidney and neurological involvement may also occur. Evaluation and treatment can be complex and often require multidisciplinary collaboration. MRI and PET/CT (with prolonged fasting) are key imaging tools in suspected cardiac sarcoidosis. Many patients do not need immunosuppressive therapy, but this review finds that methotrexate may be first-line therapy when long-term treatment is required.