Related Experiment Video
Updated: Jul 7, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Intracoronary Imaging to Guide PCI in Acute Coronary Syndromes: A Report From the BMC2 Registry
Ryan Madder1, Milan Seth2, Devraj Sukul3
1Department of Cardiovascular Medicine, William Beaumont University Hospital, Corewell Health East, Royal Oak, Michigan, USA.
Background:
Intracoronary imaging (ICI) to guide percutaneous coronary intervention (PCI) in acute coronary syndromes (ACS) carries a Class I recommendation in US guidelines.
Aims:
This analysis evaluated the frequency of ICI use among patients with ACS.
Methods:
Using data from a large statewide registry, all patients undergoing PCI between January 1, 2019, and December 31, 2024, were studied. The primary measure of interest for this analysis was the use of ICI to guide PCI, defined as the use of ICI after the decision was made to proceed with PCI. The frequency of ICI use among patients with and without ACS was compared, and the trend in ICI use in ACS patients over the study period was examined.
Results:
During the 6-year study period, 166,238 PCIs were performed at 51 non-federal hospitals in Michigan, of which 90,441 (54.4%) were performed for ACS. ICI was used to guide PCI in 25,234 (27.9%) ACS cases, which was significantly lower than ICI use in 23,999 (31.7%) non-ACS cases (p < 0.001). Over the 6-year study, a progressive and significant increase in ICI use in ACS was observed from 6.5% in the first year to 54.4% in the sixth year of the study (p < 0.001 for trend).
Conclusions:
Despite its proven benefits in ACS, ICI was used to guide PCI significantly less often among patients presenting with ACS compared with those without ACS. However, the ICI to guide PCI in ACS has increased significantly over time and at a similar pace compared to those without ACS.
Related Concept Videos
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome I: Introduction
Coronary Artery Disease V: Interprofessional Care
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Imaging Studies for Cardiovascular System V: CT