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Quantitative imaging in Nuclear Medicine
1Medical Physicist, Cancer Hospital of Thessaloniki, Greece. avatalis86@gmail.com.
Abstract:
Quantitative imaging in nuclear medicine has evolved from simple photon counting to the estimation of absolute physical quantities such as activity concentration. This transition enhances diagnostic accuracy and supports personalized treatment planning. The present work reviews the principles of quantitative imaging in SPECT and PET, highlighting major degrading factors and correction techniques. Emphasis is placed on clinical applications including dosimetry, theranostics, and functional organ assessment, as well as on dynamic imaging approaches. Finally, current developments and future perspectives toward standardized and automated quantification are discussed.
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