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Identification of the Novel HLA-C*07:1268 Allele by Next-Generation Sequencing

Ruby J Siegel1, Katrin Hacke1, Catherine L Gebhart1

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, Arizona, USA.

HLA
|August 4, 2026
PubMed

Abstract:

HLA-C*07:1268 differs from HLA-C*07:02:01:01 by one nucleotide substitution in exon 3.

Keywords:
HLA‐C*07:1268next generation sequencingnovel HLA allele

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The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
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