Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current heart valve prostheses.

E A Lefrak, A Starr

    American Family Physician
    |September 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Mechanical and tissue heart valves offer similar survival rates. Mechanical valves are durable but require blood thinners, while tissue valves have fewer blood clots but uncertain longevity.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Implementation of an automated, real-time mortality prediction tool in trauma patients: Can it do more than just predict mortality?

    Injury·2025
    Same author

    Clinical and radiographic predictors for angiography in pelvic trauma: An analysis of 1703 patients.

    Injury·2024
    Same author

    Publisher Correction: Indo-Pacific Walker circulation drove Pleistocene African aridification.

    Nature·2022
    Same author

    Indo-Pacific Walker circulation drove Pleistocene African aridification.

    Nature·2021
    Same author

    Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.

    British journal of pharmacology·2015
    Same author

    CARDIOVASCULAR SURGERY.

    A listing of research in the cardiovascular field·2014
    Same journal

    For Post-stent Patients With Atherosclerotic Coronary Vascular Disease Who Are Taking an Anticoagulant, Adding Aspirin Worsens Outcomes.

    American family physician·2026
    Same journal

    Nausea and Vomiting During Pregnancy.

    American family physician·2026
    Same journal

    Metabolic Dysfunction-Associated Steatotic Liver Disease: Diagnosis and Management.

    American family physician·2026
    Same journal

    Aerobic Exercise Is the Better Exercise Modality for Knee Osteoarthritis.

    American family physician·2026
    Same journal

    Overscreening Leads to Overdiagnosis of MASLD.

    American family physician·2026
    Same journal

    Type 2 Diabetes: Outpatient Insulin Management.

    American family physician·2026
    See all related articles

    Area of Science:

    • Cardiovascular Medicine
    • Biomedical Engineering
    • Prosthetic Devices

    Background:

    • Current heart valve prostheses include mechanical devices and tissue valves (bioprostheses).
    • Mechanical valves offer proven long-term durability but necessitate chronic anticoagulation to prevent thromboembolic complications.
    • Tissue valves present a lower risk of thromboembolism but their long-term durability remains undetermined.

    Purpose of the Study:

    • To compare the characteristics and outcomes of mechanical versus tissue heart valve prostheses.
    • To inform clinical decisions regarding prosthetic heart valve selection.

    Main Methods:

    • Review of current literature on mechanical and tissue heart valve prostheses.
    • Analysis of data regarding durability, thromboembolic complications, and survival rates.

    Related Experiment Videos

    Main Results:

    • Mechanical heart valves demonstrate established long-term durability.
    • Tissue valves are associated with a lower incidence of thromboembolism.
    • Contemporary mechanical and tissue prosthetic heart valves result in comparable survival rates.

    Conclusions:

    • Both mechanical and tissue heart valves provide similar survival outcomes.
    • The choice between mechanical and tissue valves involves balancing durability against the need for anticoagulation and the uncertainty of tissue valve longevity.