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Summary
Brain biopsy can lead to significant neurological issues. Post-biopsy EEGs revealed focal abnormalities in 75% of patients and focal seizures in 20%, highlighting potential risks of the procedure.
Area of Science:
- Neurology
- Neurosurgery
Background:
- Brain biopsy is an invasive diagnostic procedure.
- Potential complications of brain biopsy include neurological deficits and seizures.
Purpose of the Study:
- To evaluate the long-term electroencephalographic (EEG) abnormalities following brain biopsy.
- To assess the incidence of focal seizures and other EEG abnormalities after brain biopsy.
Main Methods:
- Follow-up EEG examinations were conducted on patients who had undergone brain biopsy.
- Data on focal fits (seizures) and EEG abnormalities were collected and analyzed.
Main Results:
- 20% of patients experienced focal seizures within 6 months post-biopsy.
- 75% of patients exhibited focal EEG abnormalities, including "trepanation activity" and spikes.
- Spike activity on EEG was more prevalent in patients with epilepsy.
Conclusions:
- Brain biopsy is associated with a considerable rate of irritative brain lesions.
- Performing brain biopsy necessitates careful consideration of potential risks, including induced seizures and EEG abnormalities.
- The diagnostic benefits of brain biopsy must be weighed against the risk of inducing neurological complications.