[An immunohistochemical study of prostate antigen using an enzyme-labeled antibody technique]

With an enzyme-labeled antibody technique, prostate antigen (PA) was studied immunohistochemically. PA was found to localize at epithelial cells and secretary materials in the lumen of prostatic tissue regardless of histological type. However, PA could not be detected in the interstitial area of the prostate. This technique may become useful for detection of local extension or distant metastasis of prostate cancer. An immunoelectronmicroscopical study of PA is now underway.