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The varicella-zoster virus: systemic and ocular features.
Journal of the American Academy of Dermatology
|August 1, 1984
Summary
Varicella-zoster virus infections, though often mild skin conditions, can lead to severe systemic issues. Understanding the virus aids in early detection, treatment, and prevention of complications like herpes zoster ophthalmicus.
Area of Science:
- Virology
- Immunology
- Dermatology
- Ophthalmology
Background:
- Varicella-zoster virus (VZV) infections typically present as benign skin conditions.
- However, VZV can cause severe systemic manifestations and complications.
- Current understanding of VZV has advanced significantly.
Purpose of the Study:
- To review current concepts of VZV infections.
- To detail clinical features, consequences, and management strategies.
- To specifically address herpes zoster ophthalmicus and its complications.
Main Methods:
- Comprehensive review of VZV anatomy, physiology, epidemiology, pathogenesis, pathology, immunology, and laboratory diagnosis.
- Description of clinical features and consequences of varicella and herpes zoster.
- Detailed analysis of herpes zoster ophthalmicus, including ocular implications and treatment.
Main Results:
- Improved knowledge of VZV disease.
- Enhanced detection of susceptible patients.
- Facilitated earlier use of new antiviral treatments and immunization strategies.
- Detailed understanding of herpes zoster ophthalmicus, its ocular complications, and postherpetic neuralgia management.
Conclusions:
- Advances in understanding VZV have improved patient care.
- Early detection and newer antiviral therapies are crucial.
- Herpes zoster ophthalmicus requires specialized dermatological and ophthalmological management.
- Effective prevention and treatment strategies are available for VZV infections and their complications.