[Use of the aggregate hemagglutination method for determining cholera vibrio neuraminidase]

The suitability of the aggregate hemagglutination test for neuraminidase determination in biological fluids has been evaluated. This test allows one to determine neuraminidase at a concentration of 2--4 mg/ml. The sensitivity of this test is more than 2 orders higher than that of gel diffusion technique and the thiobarbituric assay. The test has revealed that neuraminidase produced by Vibrio cholerae is not immunologically related to other kinds of neuraminidase produced by Corynebacterium diphtheriae, Clostridium perfringes and Erysepelothrix insidiosa.