Progressive cribriform and zosteriform hyperpigmentation.

Area of Science:

• Dermatology
• Clinical Pathology

Background:

• Progressive cribriform and zosteriform hyperpigmentation is a newly described skin condition.
• It is characterized by specific clinical and histological features, distinguishing it from similar dermatoses.

Observation:

• Five cases exhibited uniformly tan cribriform macular pigmentation in a zosteriform distribution.
• The onset was post-natal with gradual extension, and no history of preceding rash or inflammation was noted.
• Histopathology revealed increased basal cell layer melanin without nevus cells.

Findings:

• The described entity fulfills specific diagnostic criteria, including pigmentation pattern, histological findings, and absence of associated abnormalities.
• It differs from Becker's nevus (without hypertrichosis) and café au lait spots.
• The condition appears to be a distinct, albeit potentially common, dermatological entity.

Implications:

• Recognition of this entity is important for accurate dermatological diagnosis.
• Further research may elucidate the etiology and prevalence of progressive cribriform and zosteriform hyperpigmentation.
• This finding contributes to the understanding of pigmentary disorders.