Prognostic value of post-transplant hippurate scintigraphy

131Iodine hippurate sequential scintigrams obtained after transplantation contain prognostic information about the long-term development of a graft. Results of 131 131iodine hippurate sequential scintigrams made within 48 hours after graft implantation were compared to the graft status 2 years after transplantation. Hippurate uptake and transport were rated on a 4-step scale. Disturbed hippurate uptake and abnormal tracer transit were associated with increased frequency of early graft destruction and with a high frequency of chronic rejection. The chi-square test demonstrated a significant relationship between results of the initial hippurate scintigrams and long-term graft development.