Production of gamma (immune) interferon by a permanent human T-lymphocyte cell line

Gamma (immune, type II) interferon is an antiviral and immuno-regulatory glycoprotein usually obtained from mitogen- or antigen-induced peripheral blood or splenic mononuclear cells. A human "helper-inducer" T-lymphocyte cell line (Mo) is an inducible source of gamma interferon. Mo gamma interferon has been biochemically characterized and partially purified, and resembles the gamma interferon species derived from normal cell sources.